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autophosphorylation at T466 just isn't feasible in this geometry and also the docking web-site on helix αG with the substrate eIF2α is blocked. However, equivalent interfaces making use of the αEF and αG helices are actually noted for trans-autophosphorylation complexes of PAK159 and PknB60. - Bonus dapat dibatalkan secara otomatis dan sepihak